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KLHL20 polyclonal antibody

货号: BS32786

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS32786

Product Name :KLHL20 polyclonal antibody

Swiss-Prot :Q9Y2M5

Host :Rabbit

Reactivity :Human

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :Kelch-like protein 20: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1, leading to its degradation by the proteasome, thereby acting as a negative regulator of apoptosis . The BCR(KLHL20) E3 ubiquitin ligase complex also specifically mediates 'Lys-33'-linked ubiquitination . Involved in anterograde Golgi to endosome transport by mediating 'Lys-33'-linked ubiquitination of CORO7, promoting interaction between CORO7 and EPS15, thereby facilitating actin polymerization and post-Golgi trafficking . Also acts as a regulator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases. The BCR(KLHL20) E3 ubiquitin ligase complex acts as a regulator of neurite outgrowth by mediating ubiquiti...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of KLHL20 protein.

BiowMW :~68.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KLEIP; Kelch-like protein 20; Kelch-like ECT2-interacting protein; Kelch-like protein X

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human KLHL20.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Amphiregulin expression in A549 (A), HT29 (B) whole cell lysates.

免疫沉淀（IP）