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WDR43 polyclonal antibody

货号: BS32784

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS32784

Product Name :WDR43 polyclonal antibody

Swiss-Prot :Q15061

Host :Rabbit

Reactivity :Human

Applications :WB, IHC, FC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200), FC (1/10 - 1/50)

Background :WD repeat-containing protein 43: Ribosome biogenesis factor that coordinates hyperactive transcription and ribogenesis . Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I . Essential for stem cell pluripotency and embryonic development. In the nucleoplasm, recruited by promoter-associated/nascent transcripts and transcription to active promoters where it facilitates releases of elongation factor P-TEFb and paus...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of WDR43 protein.

BiowMW :~74.9 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KIAA0007; UTP5; WD repeat-containing protein 43

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human WDR43.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Catenin delta 1 expression in NIH3T3 (A) whole cell lysates.

Immunohistochemical analysis of Catenin delta 1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.