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EMC10 polyclonal antibody

货号: BS32758

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS32758

Product Name :EMC10 polyclonal antibody

Swiss-Prot :Q5UCC4

Host :Rabbit

Reactivity :Human

Applications :WB, IHC, FC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200), FC (1/10 - 1/50)

Background :ER membrane protein complex subunit 10: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins . Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues . Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices . It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes . By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors . By r...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of EMC10 protein.

BiowMW :~27.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C19orf63; HSM1; INM02; ER membrane protein complex subunit 10; Hematopoietic signal peptide-containing membrane domain-containing protein 1

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human EMC10.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ALDH1A2 expression in Molt4 (A) whole cell lysates.