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IFT20 polyclonal antibody

货号: BS32752

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32752

Product Name :IFT20 polyclonal antibody

Swiss-Prot :Q8IY31

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Intraflagellar transport protein 20 homolog: Part of intraflagellar transport (IFT) particles involved in ciliary process assembly . May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium . Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling . Essential for male fertility. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. May play a role in the transport of flagellar proteins ODF2 and SPAG16 to build sperm flagella and in the removal of redundant sperm cytoplasm (By similarity). Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of IFT20 protein.

BiowMW :~15.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Intraflagellar transport protein 20 homolog; hIFT20

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human IFT20.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Lamin A/C expression in mouse kidney (A), rat lung (B), rat kidney (C) whole cell lysates.

免疫沉淀（IP）