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TTI1 polyclonal antibody

货号: BS32741

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS32741

Product Name :TTI1 polyclonal antibody

Swiss-Prot :O43156

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :TELO2-interacting protein 1 homolog: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TTI1 protein.

BiowMW :~122 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KIAA0406; SMG10; TELO2-interacting protein 1 homolog; Protein SMG10

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human TTI1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HIP1 expression in A549 (A), SW480 (B), mouse brain (C) whole cell lysates.

免疫沉淀（IP）