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Semaphorin 5A polyclonal antibody

货号: BS32713

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32713

Product Name :Semaphorin 5A polyclonal antibody

Swiss-Prot :Q13591

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Semaphorin-5A: Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of Semaphorin 5A protein.

BiowMW :~121 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SEMAF; Semaphorin-5A; Semaphorin-F; Sema F

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human Semaphorin 5A.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Adenylate Cyclase 9 expression in HeLa (A), SP2/0 (B), H9C2 (C) whole cell lysates.

免疫沉淀（IP）