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IFI27 polyclonal antibody

货号: BS32698

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32698

Product Name :IFI27 polyclonal antibody

Swiss-Prot :P40305

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Interferon alpha-inducible protein 27, mitochondrial: Probable adapter protein involved in different biological processes . Part of the signaling pathways that lead to apoptosis . Involved in type-I interferon-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9 . Also functions in TNFSF10-induced apoptosis . May also have a function in the nucleus, where it may be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors . May thereby play a role in the vascular response to injury (By similarity). In the innate immune response, has an antiviral activity towards hepatitis C virus/HCV . May prevent the replication of the virus by recruiting both the hepatitis C virus non-structural protein 5A/NS5A and the...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of IFI27 protein.

BiowMW :~11.5 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Interferon alpha-inducible protein 27, mitochondrial; p27; Interferon alpha-induced 11.5 kDa protein; Interferon-stimulated gene 12a protein; ISG12(a)

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human IFI27.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PDPK1 expression in Hela (A), PC12 (B) whole cell lysates.