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CH25H polyclonal antibody

货号: BS32697

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS32697

Product Name :CH25H polyclonal antibody

Swiss-Prot :O95992

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Cholesterol 25-hydroxylase: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes . Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (By similarity). May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing . As an interferon-stimulated gene, has broad antiviral activities against a wide range of enveloped viruses, such as vesicular stomatitis virus (VSV) and SARS coronavirus-2 (SARS-CoV-2). Its product, 25-hydroxycholesterol, activates the ER-localized enzyme ACAT to induce interna...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CH25H protein.

BiowMW :~31.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Cholesterol 25-hydroxylase; Cholesterol 25-monooxygenase; h25OH

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human CH25H.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Telomerase expression in Hela (A), HEK293T (B), L929 (C) whole cell lysates.

免疫沉淀（IP）