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TMEM97 polyclonal antibody

货号: BS32598

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS32598

Product Name :TMEM97 polyclonal antibody

Swiss-Prot :Q5BJF2

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Sigma intracellular receptor 2: Sigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking, and stabilization of receptors at the cell surface, thereby contributing to the maintenance of cellular homeostasis. Forms a ternary complex with PGRMC1 and LDLR at the plasma membrane, promoting LDLR-mediated internalization of LDL cholesterol . Reduces the availability of the lysosomal sterol transporter NPC1, likely through direct interaction, thereby regulating lipid transport, including cholesterol and LBPA, outside of late endosome/lysosome . Binds the regio- and stereoselective oxysterol 20(S)-hydroxycholesterol (20(S)-OHC). Ligand binding enhances association with NPC1 and modulates TMEM97-containing protein complexes involving PGRMC1 and TSPO, consistent with a role in...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TMEM97 protein.

BiowMW :~20.8 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MAC30; Transmembrane protein 97; Protein MAC30

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human TMEM97.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of MSK1 expression in HEK293T (A), mouse brain (B) whole cell lysates.

免疫沉淀（IP）