产品类别

联系我们

电话:18013895086

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

SPPL2B polyclonal antibody

货号: BS32588

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS32588

Product Name :SPPL2B polyclonal antibody

Swiss-Prot :Q8TCT7

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Signal peptide peptidase-like 2B: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing . Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus . May play a role in the regulation of innate and adaptive immunity . Catalyzes the intramembrane cleavage of the simian foamy virus processed leader peptide gp18 of the envelope glycoprotein gp130 dependently of prior ectodomain shedding by furin or furin-like proprotein convertase (PC)-mediated cleavage proteolysis

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SPPL2B protein.

BiowMW :~64.6 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IMP4; KIAA1532; PSL1; Signal peptide peptidase-like 2B; SPP-like 2B; SPPL2b; Intramembrane protease 4; IMP-4; Presenilin homologous protein 4; PSH4; Presenilin-like protein 1

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human SPPL2B.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of c-Jun expression in Hela (A), H1688 (B) whole cell lysates.