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TPR polyclonal antibody

货号: BS32571

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32571

Product Name :TPR polyclonal antibody

Swiss-Prot :P12270

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Nucleoprotein TPR: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs, plays a role in the establishment of nuclear-peripheral chromatin compartmentalization in interphase, and in the mitotic spindle checkpoint signaling during mitosis. Involved in the quality control and retention of unspliced mRNAs in the nucleus; in association with NUP153, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Negatively regulates both the association of CTE-containing mRNA with large polyribosomes and translation initiation. Does not play any role in Rev response element (RRE)-mediated export of unspliced mRNAs. Implicated in nuclea...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TPR protein.

BiowMW :~267 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Nucleoprotein TPR; Megator; NPC-associated intranuclear protein; Translocated promoter region protein

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human TPR.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of NPC1 expression in Hela (A) whole cell lysates.

免疫沉淀（IP）