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PHACTR4 polyclonal antibody

货号: BS32547

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS32547

Product Name :PHACTR4 polyclonal antibody

Swiss-Prot :Q8IZ21

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Phosphatase and actin regulator 4: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of PHACTR4 protein.

BiowMW :~78.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Phosphatase and actin regulator 4

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human PHACTR4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of SLC4A1 expression in Red blood (A) whole cell lysates.

免疫沉淀（IP）