Product Name :PGP polyclonal antibody
Applications :WB, IHC, FC
Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200), FC (1/10 - 1/50)
Background :Phosphoglycolate phosphatase: Phosphatase with activity against multiple substrates . Acts as a metabolite repair enzyme which eliminates toxic glycolytic side products . Dephosphorylates 2-phosphoglycolate which is generated during the repair of oxidative DNA lesions . This controls triosephosphate isomerase activity, glycerolipid partitioning and cell proliferation in the embryo and is required for embryonic development (By similarity). Dephosphorylates 4-phosphoerythronate, a side product which is produced by GAPDH and which inhibits 6-phosphogluconate dehydrogenase . Dephosphorylation of 4-phosphoerythronate prevents the accumulation of high 4-phosphoerythronate levels which would otherwise inhibit the pentose phosphate pathway . Dephosphorylates 2-phospho-L-lactate which is a product of a pyruvate kinase side reaction . This prevents the inhibition of fructose-2,6-bisphosphate production and allows glycolysis...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of PGP protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Phosphoglycolate phosphatase; PGP; PGPase
Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human PGP.
Modification :Unmodification
