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MICAL2 polyclonal antibody

货号: BS32524

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32524

Product Name :MICAL2 polyclonal antibody

Swiss-Prot :O94851

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :[F-actin]-monooxygenase MICAL2: Methionine monooxygenase that promotes depolymerization of F-actin by mediating oxidation of residues 'Met-44' and 'Met-47' on actin to form methionine-sulfoxide, resulting in actin filament disassembly and preventing repolymerization . Regulates the disassembly of branched actin networks also by oxidizing ARP3B-containing ARP2/3 complexes leading to ARP3B dissociation from the network . Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MICAL2 protein.

BiowMW :~219 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KIAA0750; MICAL2PV1; MICAL2PV2; Protein-methionine sulfoxide oxidase MICAL2; Molecule interacting with CasL protein 2; MICAL-2

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human MICAL2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of BAI1 expression in 293T (A), mouse brain (B), rat brain (C) whole cell lysates.

免疫沉淀（IP）