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PLCZ1 polyclonal antibody

货号: BS32519

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32519

Product Name :PLCZ1 polyclonal antibody

Swiss-Prot :Q86YW0

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of PLCZ1 protein.

BiowMW :~70.4 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; PLC-zeta-1; Testis-development protein NYD-SP27

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human PLCZ1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD8a expression in Raji (A) whole cell lysates.