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TCHP polyclonal antibody

货号: BS32516

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32516

Product Name :TCHP polyclonal antibody

Swiss-Prot :Q9BT92

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Trichoplein keratin filament-binding protein: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells . Is a negative regulator of ciliogenesis

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TCHP protein.

BiowMW :~61.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Trichoplein keratin filament-binding protein; Protein TCHP; Mitochondrial protein with oncostatic activity; Mitostatin; Tumor suppressor protein

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human TCHP.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PARP1 expression in Hela (A), 293T (B), Jurkat (C) whole cell lysates.