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DZIP1 polyclonal antibody

货号: BS32486

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS32486

Product Name :DZIP1 polyclonal antibody

Swiss-Prot :Q86YF9

Host :Rabbit

Reactivity :Human

Applications :WB, IHC, FC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200), FC (1/10 - 1/50)

Background :Cilium assembly protein DZIP1: Molecular adapter that recruits protein complexes required for cilium assembly and function to the cilium basal body . At the exit of mitosis, localizes to the basal body and ciliary base of the forming primary cilium where it recruits and activates RAB8A to direct vesicle-mediated transport of proteins to the cilium (By similarity). Also recruits the BBSome, a complex involved in cilium biogenesis, by bridging it to PCM1 at the centriolar satellites of the cilium . It is also required for the recruitment to the cilium basal body of the intraflagellar transport (IFT) machinery as well as the ciliary appendage proteins CEP164 and NINEIN (By similarity). Functions as a regulator of Hedgehog signaling both through its role in cilium assembly but also probably through its ability to retain GLI3 within the cytoplasm (By similarity). It is involved in spermatogenesis through its role in org...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of DZIP1 protein.

BiowMW :~98.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DZIP; DZIP2; KIAA0996; Zinc finger protein DZIP1; DAZ-interacting protein 1/2

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human DZIP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD4 expression in THP1 (A), mouse spleen (B) whole cell lysates.

免疫沉淀（IP）