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ARPC1B polyclonal antibody

货号: BS32477

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32477

Product Name :ARPC1B polyclonal antibody

Swiss-Prot :O15143

Host :Rabbit

Reactivity :Human

Applications :WB, IHC, FC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200), FC (1/10 - 1/50)

Background :Actin-related protein 2/3 complex subunit 1B: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) . The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility . In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA . The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ARPC1B protein.

BiowMW :~41.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ARC41; Actin-related protein 2/3 complex subunit 1B; Arp2/3 complex 41 kDa subunit; p41-ARC

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human ARPC1B.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PSMD9 expression in Jurkat (A), A549 (B) whole cell lysates.

免疫沉淀（IP）