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NME5 polyclonal antibody

货号: BS32466

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS32466

Product Name :NME5 polyclonal antibody

Swiss-Prot :P56597

Host :Rabbit

Reactivity :Human

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :Nucleoside diphosphate kinase 5: Functions as part of axonemal radial spoke complexes, which play an important part in the motility of sperm and cilia (By similarity). In vitro, does not display nucleoside diphosphate kinase (NDPK) activity (Probable) . Exhibits a 3'-5'-DNA exonuclease activity that removes single nucleotides from the 3' terminus of single-stranded DNA substrates and digests overhanging mismatched 3' termini from double-stranded DNA substrates, possibly participating in DNA nucleolytic processing . Confers protection from cell death mediated by BAX and alters the cellular levels of several antioxidant enzymes, including GPX5 (By similarity). Might be involved in spermiogenesis by enhancing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of NME5 protein.

BiowMW :~24.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Nucleoside diphosphate kinase homolog 5; NDK-H 5; NDP kinase homolog 5; Inhibitor of p53-induced apoptosis-beta; IPIA-beta; Testis-specific nm23 homolog; nm23-H5

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human NME5.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Pendrin expression in human kidney (A), rat kidney (B) whole cell lysates.