Product Name :EHD3 polyclonal antibody
Applications :WB, IHC, FC
Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200), FC (1/10 - 1/50)
Background :EH domain-containing protein 3: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis . In vitro causes tubulation of endocytic membranes . Binding to phosphatidic acid induces its membrane tubulation activity (By similarity). Plays a role in endocytic transport. Involved in early endosome to recycling endosome compartment (ERC), retrograde early endosome to Golgi, and endosome to plasma membrane (rapid recycling) protein transport. Involved in the regulation of Golgi maintenance and morphology . Involved in the recycling of internalized D1 dopamine receptor . Plays a role in cardiac protein trafficking probably implicating ANK2 . Involved in the ventricular membrane targeting of SLC8A1 and CACNA1C and probably the atrial membrane localization of CACNA1GG and CACNA1H implicated in the regulation of atrial myocyte excitability and cardiac conduction (By similarity). In...
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of EHD3 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :EHD2; PAST3; EH domain-containing protein 3; PAST homolog 3
Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human EHD3.
Modification :Unmodification
