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BRDT polyclonal antibody

货号: BS32441

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS32441

Product Name :BRDT polyclonal antibody

Swiss-Prot :Q58F21

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Bromodomain testis-specific protein: Testis-specific chromatin protein that specifically binds histone H4 acetylated at 'Lys-5' and 'Lys-8' (H4K5ac and H4K8ac, respectively) and plays a key role in spermatogenesis . Required in late pachytene spermatocytes: plays a role in meiotic and post-meiotic cells by binding to acetylated histones at the promoter of specific meiotic and post-meiotic genes, facilitating their activation at the appropriate time . In the post-meiotic phase of spermatogenesis, binds to hyperacetylated histones and participates in their general removal from DNA . Also recognizes and binds a subset of butyrylated histones: able to bind histone H4 butyrylated at 'Lys-8' (H4K8ac), while it is not able to bind H4 butyrylated at 'Lys-5' (H4K5ac) (By similarity). Also acts as a component of the splicing machinery in pachytene spermatocytes and round spermatids and participates in 3'-UTR truncation of specific...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of BRDT protein.

BiowMW :~108 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Bromodomain testis-specific protein; Cancer/testis antigen 9; CT9; RING3-like protein

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human BRDT.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of LRP6 expression in rat lung (A) whole cell lysates.

免疫沉淀（IP）