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FBXO9 polyclonal antibody

货号: BS32385

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32385

Product Name :FBXO9 polyclonal antibody

Swiss-Prot :Q9UK97

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :F-box only protein 9: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability . Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation. In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex. As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1 . Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation b...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of FBXO9 protein.

BiowMW :~52.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FBX9; VCIA1; F-box only protein 9; Cross-immune reaction antigen 1; Renal carcinoma antigen NY-REN-57

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human FBXO9.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Tyrosinase expression in human melanoma (A) whole cell lysates.

免疫沉淀（IP）