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CHST4 polyclonal antibody

货号: BS32364

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32364

Product Name :CHST4 polyclonal antibody

Swiss-Prot :Q8NCG5

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Carbohydrate sulfotransferase 4: Sulfotransferase involved in SELL/L-selectin ligand biosynthesis pathway. Catalyzes the transfer of the sulfate group from 3'-phospho-5'-adenylyl sulfate (PAPS) onto the hydroxyl group at C-6 position of the non-reducing N-acetylglucosamine (GlcNAc) residue within O-linked mucin-type glycans. Contributes to generate sialyl 6-sulfo Lewis X determinant (also known as MECA-79 epitope) for SELL recognition, a prerequisite for continuous lymphocyte homing into peripheral lymph nodes and antigen immune surveillance . Transfers the sulfate group primarily on core 2 GlcNAcbeta1-6(Galbeta1-3)GalNAcalphaSer/Thr and extended core 1 GlcNAcbeta1-3Galbeta1-3GalNAcalphaSer/Thr based O-linked glycans on CD34 and GLYCAM1 peripheral node addressins (PNAds) expressed on the lumenal side of high endothelial venules (HEVs) . The recognition of PNAds by SELL initiates a multistep process comprising tetheri...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CHST4 protein.

BiowMW :~45.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Carbohydrate sulfotransferase 4; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; GST-3; High endothelial cells N-acetylglucosamine 6-O-sulfotransferase; HEC-GlcNAc6ST; L-selectin ligand sulfotransferase; LSST; N-acetylglucosamine 6-O-sulfotransferase 2; GlcNAc6ST-2; Gn6st-2

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human CHST4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of p53 (Phospho-S6) expression in A549 (A), HEK293T (B), rat kidney (C), mouse kidney (D) whole cell lysates.