产品类别

联系我们

电话:18013895086

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

TRIM6 polyclonal antibody

货号: BS32271

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS32271

Product Name :TRIM6 polyclonal antibody

Swiss-Prot :Q9C030

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Tripartite motif-containing protein 6: E3 ubiquitin ligase that plays a crucial role in the activation of the IKBKE-dependent branch of the type I interferon signaling pathway . In concert with the ubiquitin-conjugating E2 enzyme UBE2K, synthesizes unanchored 'Lys-48'-linked polyubiquitin chains that promote the oligomerization and autophosphorylation of IKBKE leading to stimulation of an antiviral response . Also ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells (By similarity). Promotes the association of unanchored 'Lys-48'-polyubiquitin chains with DHX16 leading to enhanced RIGI-mediated innate antiviral immune response

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TRIM6 protein.

BiowMW :~56.4 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RNF89; Tripartite motif-containing protein 6; RING finger protein 89

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human TRIM6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HSP70 expression in A549 (A), H1792 (B), LO2 (C), mouse liver (D), mouse kidney (E), rat liver (F), rat kidney (G) whole cell lysates.