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CBWD6 polyclonal antibody

货号: BS32213

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS32213

Product Name :CBWD6 polyclonal antibody

Swiss-Prot :Q4V339

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Zinc-regulated GTPase metalloprotein activator 1F: Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them (By similarity). Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation . Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1 (By similarity). After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1F to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis (By similarity). GTP/GDP exchange is required for release of active METAP1 (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CBWD6 protein.

BiowMW :~44.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :COBW domain-containing protein 6; Cobalamin synthase W domain-containing protein 6

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human CBWD6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of IRE1 expression in HEK293T (A), mouse liver (B), rat liver (C) whole cell lysates.

免疫沉淀（IP）