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MKRN1 polyclonal antibody

货号: BS32207

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS32207

Product Name :MKRN1 polyclonal antibody

Swiss-Prot :Q9UHC7

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :E3 ubiquitin-protein ligase makorin-1: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MKRN1 protein.

BiowMW :~53.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RNF61; E3 ubiquitin-protein ligase makorin-1; RING finger protein 61

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human MKRN1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of TRIM27 expression in Jurkat (A), mouse testis (B) whole cell lysates.

免疫沉淀（IP）