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ZNF410 polyclonal antibody

货号: BS32179

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32179

Product Name :ZNF410 polyclonal antibody

Swiss-Prot :Q86VK4

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Zinc finger protein 410: Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3', and is specifically required to silence expression of fetal hemoglobin in adult erythroid cells . Prevents expression of fetal hemoglobin genes HBG1 and HBG2 through CHD4: acts as a direct transcriptional activator of CHD4, a central component of the NuRD complex that represses transcription of fetal hemoglobin genes HBG1 and HBG2 in erythroid cells . May also activate transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence . May activate transcription of the gap junction gene GJC1, perhaps in response to increasing glucose . However, recent studies suggest that ZNF410 is dedicated to regulate expression of a single gene: CHD4

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ZNF410 protein.

BiowMW :~52.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :APA1; Zinc finger protein 410; Another partner for ARF 1; Zinc finger protein APA-1

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human ZNF410.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Insulin expression in MIN6 (A) whole cell lysates.

免疫沉淀（IP）