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EXOSC6 polyclonal antibody

货号: BS32148

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32148

Product Name :EXOSC6 polyclonal antibody

Swiss-Prot :Q5RKV6

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Exosome complex component MTR3: Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs co...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of EXOSC6 protein.

BiowMW :~28.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MTR3; Exosome complex component MTR3; Exosome component 6; mRNA transport regulator 3 homolog; hMtr3; p11

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human EXOSC6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of IDH1 expression in A549 (A), Raji (B), mouse kidney (C), mouse liver (D) whole cell lysates.

免疫沉淀（IP）