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MMS19 polyclonal antibody

货号: BS32123

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32123

Product Name :MMS19 polyclonal antibody

Swiss-Prot :Q96T76

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :MMS19 nucleotide excision repair protein homolog: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity . In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER), homologous recombination-mediated double-strand break DNA repair, DNA replication and RNA polymerase II (POL II) transcription . As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur (Fe-S) cluster assembly into ERCC2/XPD . Together with CIAO2, facilitates the transfer of Fe-S clusters to the motor protein KIF4A, which ensures proper localization o...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of MMS19 protein.

BiowMW :~113 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MMS19L; MMS19 nucleotide excision repair protein homolog; hMMS19; MET18 homolog; MMS19-like protein

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human MMS19.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Gamma-enolase expression in HeLa (A) whole cell lysates.

免疫沉淀（IP）