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ZFP57 polyclonal antibody

货号: BS32062

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32062

Product Name :ZFP57 polyclonal antibody

Swiss-Prot :Q9NU63

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Zinc finger protein 57 homolog: Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs) . Acts together with ZNF445, but ZNF445 seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant role in imprinting maintenance . Required for the establishment of maternal methylation imprints at SNRPN locus. Acts as a transcriptional repressor in Schwann cells. Binds to a 5'-TGCCGC-3' consensus sequence and recognizes the methylated CpG within this element (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ZFP57 protein.

BiowMW :~51.9 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C6orf40; ZNF698; Zinc finger protein 57 homolog; Zfp-57; Zinc finger protein 698

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human ZFP57.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD32a expression in K562 (A), mouse muscle (B), rat muscle (C) whole cell lysates.

免疫沉淀（IP）