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TIPRL polyclonal antibody

货号: BS32037

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS32037

Product Name :TIPRL polyclonal antibody

Swiss-Prot :O75663

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :TIP41-like protein: May be a allosteric regulator of serine/threonine-protein phosphatase 2A (PP2A). Isoform 1 inhibits catalytic activity of the PP2A(D) core complex in vitro. The PP2A(C):TIPRL complex does not show phosphatase activity. Acts as a negative regulator of serine/threonine-protein phosphatase 4 probably by inhibiting the formation of the active PPP4C:PPP4R2 complex; the function is proposed to implicate it in DNA damage response by promoting H2AX phosphorylated on Ser-140 (gamma-H2AX). May play a role in the regulation of ATM/ATR signaling pathway controlling DNA replication and repair

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TIPRL protein.

BiowMW :~31.4 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TIP41-like protein; Putative MAPK-activating protein PM10; Type 2A-interacting protein; TIP

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human TIPRL.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of NTN3 expression in CEM (A) whole cell lysates.

免疫沉淀（IP）