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ZNF385A polyclonal antibody

货号: BS32003

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS32003

Product Name :ZNF385A polyclonal antibody

Swiss-Prot :Q96PM9

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Zinc finger protein 385A: RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction. Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes. May also regulate the ubiquitination and stability of CDKN1A p...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ZNF385A protein.

BiowMW :~40.5 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HZF; RZF; ZNF385; Zinc finger protein 385A; Hematopoietic zinc finger protein; Retinal zinc finger protein

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human ZNF385A.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Vimentin expression in Jurkat (A), K562 (B), SKNSH (C), SHSY5Y (D), Hela (E), NIH/3T3 (F), C6 (G), RAW264.7 (H) whole cell lysates.