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CERS6 polyclonal antibody

货号: BS31984

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31984

Product Name :CERS6 polyclonal antibody

Swiss-Prot :Q6ZMG9

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Ceramide synthase 6: Ceramide synthase that catalyzes the transfer of the fatty acyl chain from acyl-CoA to a sphingoid base, with high selectivity toward palmitoyl-CoA (hexadecanoyl-CoA; C16:0-CoA) . Can use different sphingoid bases as substrates for ceramide synthesis, such as sphinganine in de novo synthesis, and sphing-4E-enine (sphingosine), (4R)-hydroxysphinganine (phytosphingosine) or sphinga-4E,14Z-dienine in salvage pathways . Other fatty acyl-CoAs such as long-chain saturated stearoyl-CoA (octadecanoyl-CoA; C18:0-CoA), myristoyl-CoA (tetradecanoyl-CoA; C14:0-CoA), and monounsaturated oleoyl-CoA (9Z-octadecenoyl-CoA; C18:1-CoA) can also act as acyl donors, but with less efficiency than hexadecanoyl-CoA . Ceramides generated by CERS6 play a role in inflammatory response (By similarity). Acts as a regulator of metabolism and hepatic lipid accumulation (By similarity). Under high fat diet, palmitoy...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CERS6 protein.

BiowMW :~44.9 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LASS6; Ceramide synthase 6; CerS6; LAG1 longevity assurance homolog 6

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human CERS6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of DRR1 expression in K562 (A) whole cell lysates.

免疫沉淀（IP）