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KLHL2 polyclonal antibody

货号: BS31973

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS31973

Product Name :KLHL2 polyclonal antibody

Swiss-Prot :O95198

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Kelch-like protein 2: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, WNK1, WNK3 and WNK4, leading most often to their proteasomal degradation . The BCR(KLHL2) complex catalyzes ubiquitination and degradation of NPTXR (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4 . Plays a role in the reorganization of the actin cytoskeleton . Promotes growth of cell projections in oligodendrocyte precursors

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of KLHL2 protein.

BiowMW :~66.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Kelch-like protein 2; Actin-binding protein Mayven

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human KLHL2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of EIF1AY expression in MCF7 (A), Jurkat (B), NIH3T3 (C), mouse brain (D), rat brain (E) whole cell lysates.

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