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CACFD1 polyclonal antibody

货号: BS31953

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31953

Product Name :CACFD1 polyclonal antibody

Swiss-Prot :Q9UGQ2

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Calcium channel flower homolog: Transmembrane protein which mediates synaptic endocytosis and fitness-based cell culling . In response to different stimulus strengths, controls two major modes of synaptic vesicle (SV) retrieval in hippocampal neurons; Clathrin-mediated endocytosis (CME) in response to mild stimulation and activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (By similarity). In cytotoxic T-lymphocytes (CTLs) facilitates calcium-dependent endocytosis of cytotoxic granules at the immuno synapse (By similarity). Different isoforms work as fitness fingerprints in 'loser' and 'winner' cells and thereby mediate win/lose decisions as part of the cell competition process

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of CACFD1 protein.

BiowMW :~18.5 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C9orf7; Calcium channel flower homolog; Calcium channel flower domain-containing protein 1

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human CACFD1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Beta-glucosidase 2 expression in A431 (A) whole cell lysates.

免疫沉淀（IP）