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KPTN polyclonal antibody

货号: BS31915

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS31915

Product Name :KPTN polyclonal antibody

Swiss-Prot :Q9Y664

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :KICSTOR complex protein kaptin: As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of KPTN protein.

BiowMW :~48.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Kaptin; Actin-associated protein 2E4

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human KPTN.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CREB (Phospho-S133) expression in HeLa treated with Calyculin A (A) whole cell lysates.

免疫沉淀（IP）