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GRHL3 polyclonal antibody

货号: BS31894

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS31894

Product Name :GRHL3 polyclonal antibody

Swiss-Prot :Q8TE85

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Grainyhead-like protein 3 homolog: Transcription factor playing important roles in primary neurulation and in the differentiation of stratified epithelia of both ectodermal and endodermal origin (By similarity). Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' acting as an activator and repressor on distinct target genes . xhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair (By similarity). Exhibits functional redundancy with GRHL2 in epidermal morphogenetic events and epidermal wound repair but is essential to form the epidermal barrier with TGM3 as critical direct target gene among others. Despite being dispensable during normal epidermal homeostasis in the adulthood, is again required for barrier repair after immune-mediated epidermal damage, regulates distinct gene batteries in embryonic epidermal differentiation and adult epidermal barrier reformation af...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of GRHL3 protein.

BiowMW :~70.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SOM; TFCP2L4; Grainyhead-like protein 3 homolog; Sister of mammalian grainyhead; Transcription factor CP2-like 4

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human GRHL3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PKC beta (Phospho-S661) expression in mouse brain (A) whole cell lysates.

免疫沉淀（IP）