产品类别

联系我们

电话:18013895086

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

KIDINS220 polyclonal antibody

货号: BS31872

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS31872

Product Name :KIDINS220 polyclonal antibody

Swiss-Prot :Q9ULH0

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Kinase D-interacting substrate of 220 kDa: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of KIDINS220 protein.

BiowMW :~197 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ARMS; KIAA1250; Kinase D-interacting substrate of 220 kDa; Ankyrin repeat-rich membrane-spanning protein

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human KIDINS220.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of B-RAF expression in HL60 (A), HeLa (B), NIH3T3 (C) whole cell lysates.

免疫沉淀（IP）