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ZDHHC3 polyclonal antibody

货号: BS31864

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS31864

Product Name :ZDHHC3 polyclonal antibody

Swiss-Prot :Q9NYG2

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Palmitoyltransferase ZDHHC3: Golgi-localized palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates . Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity). Plays an important role in G protein-coupled receptor signaling pathways involving GNAQ and potentially other heterotrimeric G proteins by regulating their dynamic association with the plasma membrane . Palmitoylates ITGA6 and ITGB4, thereby regulating the alpha-6/beta-4 integrin localization, expression and function in cell adhesion to laminin . Plays a role in the TRAIL-activated apoptotic signaling pathway most probably through the palmitoylation and localization to the plasma membrane of TNFRSF10A . In the brain, by palmitoylating the gamma subunit GABRG2 of GABA(A) receptors and r...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of ZDHHC3 protein.

BiowMW :~34.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ZNF373; Palmitoyltransferase ZDHHC3; Protein DHHC1; Zinc finger DHHC domain-containing protein 3; DHHC-3; Zinc finger protein 373

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human ZDHHC3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CCL4 expression in THP1 treated with PMA, LPS, Brefeldin A (A) whole cell lysates.

免疫沉淀（IP）