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TMC6 polyclonal antibody

货号: BS31825

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS31825

Product Name :TMC6 polyclonal antibody

Swiss-Prot :Q7Z403

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Transmembrane channel-like protein 6: Acts as a regulatory protein involved in the regulation of numerous cellular processes . Together with its homolog TMC8/EVER2, forms a complex with CIB1 in lymphocytes and keratynocytes where TMC6 and TMC8 stabilize CIB1 and reciprocally . Together with TMC8, also forms a complex with and activates zinc transporter ZNT1 at the ER membrane of keratynocytes, thereby facilitating zinc uptake into the ER . Down-regulates the activity of transcription factors induced by zinc and cytokines . Also plays a role in thermal sensation by inhibiting the M-channel (KCNQ2-KCNQ3 channel) current in primary sensory neurons (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TMC6 protein.

BiowMW :~90.0 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EVER1; EVIN1; Transmembrane channel-like protein 6; Epidermodysplasia verruciformis protein 1; Protein LAK-4

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human TMC6.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ASS1 expression in MCF7 (A), mouse liver (B), mouse kidney (C), rat liver (D), rat kidney (E) whole cell lysates.

免疫沉淀（IP）