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TIAM2 polyclonal antibody

货号: BS31793

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS31793

Product Name :TIAM2 polyclonal antibody

Host :Rabbit

Reactivity :Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Rho guanine nucleotide exchange factor TIAM2: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates specifically RAC1, but not CDC42 and RHOA. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TIAM2 protein.

BiowMW :~193 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KIAA2016; STEF; T-lymphoma invasion and metastasis-inducing protein 2; TIAM-2; SIF and TIAM1-like exchange factor

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human TIAM2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of ATF1 (Phospho-S63) expression in HEK293T (A), NIH3T3 (B), mouse kidney (C) whole cell lysates.

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