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EMP2 polyclonal antibody

货号: BS31787

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31787

Product Name :EMP2 polyclonal antibody

Host :Rabbit

Reactivity :Mouse

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :Epithelial membrane protein 2: Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation . Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation . Facilitates surface trafficking and the formation of lipid rafts bearing GPI-anchor proteins . Regulates surface expression of MHC1 and ICAM1 proteins increasing susceptibility to T-cell mediated cytotoxicity . Regulates the plasma membrane expression of the integrin heterodimers ITGA6-ITGB1, ITGA5-ITGB3 and ITGA5-ITGB1 resulting in modulation of cell-matrix adhesion ....

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of EMP2 protein.

BiowMW :~19.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :XMP; Epithelial membrane protein 2; EMP-2; Protein XMP

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human EMP2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD138 expression in Hela (A), HepG2 (B) whole cell lysates.

免疫沉淀（IP）