Product Name :METTL23 polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Histone-arginine methyltransferase METTL23: Histone methyltransferase that dimethylates histone H3 at 'Arg-17', forming asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling (By similarity). Maternal factor involved in epigenetic chromatin reprogramming of the paternal genome in the zygote: mediates H3R17me2a, promoting histone H3.3 incorporation in the male pronucleus, leading to TET3 recruitment and subsequent DNA demethylation (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of METTL23 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C17orf95; Methyltransferase-like protein 23
Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human METTL23.
Modification :Unmodification