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JPH2 polyclonal antibody

货号: BS31773

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31773

Product Name :JPH2 polyclonal antibody

Swiss-Prot :Q9BR39

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Junctophilin-2: Membrane-binding protein that provides a structural bridge between the plasma membrane and the sarcoplasmic reticulum and is required for normal excitation-contraction coupling in cardiomyocytes . Provides a structural foundation for functional cross-talk between the cell surface and intracellular Ca(2+) release channels by maintaining the 12-15 nm gap between the sarcolemma and the sarcoplasmic reticulum membranes in the cardiac dyads (By similarity). Necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release (By similarity). Contributes to the construction of skeletal muscle triad junctions (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of JPH2 protein.

BiowMW :~74.2 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :JP2; Junctophilin-2; JP-2; Junctophilin type 2

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human JPH2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of HO-1 expression in Hela (A), mouse spleen (B), rat spleen (C) whole cell lysates.

免疫沉淀（IP）