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B3GNT1 polyclonal antibody

货号: BS31746

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31746

Product Name :B3GNT1 polyclonal antibody

Swiss-Prot :O43505

Host :Rabbit

Reactivity :Human

Applications :WB, IHC

Application_all :WB (1/500 - 1/1000), IHC (1/50 - 1/200)

Background :Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1) . Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan . Phosphorylated O-mannosyl glycan is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity . Required for axon guidance; via its function in O-mannosylation of alpha-dystroglycan (DAG1) (By similarity)

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of B3GNT1 protein.

BiowMW :~47.1 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :B3GNT6; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human B3GNT1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of E3BP expression in HepG2 (A), MCF7 (B), mouse testis (C), mouse brain (D), rat kidney (E) whole cell lysates.