Product Name :UNC5D polyclonal antibody
Application_all :WB (1/500 - 1/1000)
Background :Netrin receptor UNC5D: Receptor for the netrin NTN4 that promotes neuronal cell survival (By similarity). Plays a role in cell-cell adhesion and cell guidance. Receptor for netrin involved in cell migration. Plays a role in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding (By similarity). May play a role in apoptosis in response to DNA damage . It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand . Mediates cell-cell adhesion via its interaction with FLRT3 on an adjacent cell (By similarity)
Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Purification&Purity :The antibody was purified by immunogen affinity chromatography.
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Recognizes endogenous levels of UNC5D protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :KIAA1777; UNC5H4; Netrin receptor UNC5D; Protein unc-5 homolog 4; Protein unc-5 homolog D
Immunogen :A synthetic peptide encompassing a sequence within the Central region of human UNC5D.
Modification :Unmodification