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TTLL4 polyclonal antibody

货号: BS31670

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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No. :BS31670

Product Name :TTLL4 polyclonal antibody

Swiss-Prot :Q14679

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Tubulin monoglutamylase TTLL4: Monoglutamylase which modifies both tubulin and non-tubulin proteins, adding a single glutamate on the gamma-carboxyl group of specific glutamate residues of target proteins. Involved in the side-chain initiation step of the polyglutamylation reaction but not in the elongation step. Preferentially modifies beta-tail tubulin over the alpha-tubulin. Monoglutamylates nucleosome assembly proteins NAP1L1 and NAP1L4. Monoglutamylates nucleotidyltransferase CGAS, leading to inhibition of CGAS catalytic activity, thereby preventing antiviral defense function. Involved in KLF4 glutamylation which impedes its ubiquitination, thereby leading to somatic cell reprogramming, pluripotency maintenance and embryogenesis

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TTLL4 protein.

BiowMW :~133 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :KIAA0173; Tubulin polyglutamylase TTLL4; Tubulin--tyrosine ligase-like protein 4

Immunogen :A synthetic peptide encompassing a sequence within the Central region of human TTLL4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of TIP47 expression in Hela (A), K562 (B), Daudi (C) whole cell lysates.

免疫沉淀（IP）