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SAMD8 polyclonal antibody

货号: BS31621

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31621

Product Name :SAMD8 polyclonal antibody

Swiss-Prot :Q96LT4

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Sphingomyelin synthase-related protein 1: Has phospholipase C (PLC) activity . Shows specificity for phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE), hydrolyzing PE to produce phosphoethanolamine and diacylglycerol (1,2-diacyl-sn-glycerol, DAG) . This reaction might act as a regulatory switch to activate serine palmitoyltransferase (SPT) and promote sphingolipid metabolism (By similarity). Can also function as a ceramide phosphoethanolamine (N-acylsphingoid 1-phosphoethanolamine, CPE) synthase when intracellular ceramide levels are elevated . Binds the headgroup from PE, which is smaller and more hydrophilic than the phosphocholine headgroup transferred in the canonical sphingomyelin synthesis (SMS) reaction by SMS1 or SMS2, and transfers it on to the primary hydroxyl of a ceramide in the lumen of the endoplasmic reticulum . Plays a role as a ceramide sensor, helping to regulate ceramide homeostasis...

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SAMD8 protein.

BiowMW :~48.3 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Sphingomyelin synthase-related protein 1; SMSr; Ceramide phosphoethanolamine synthase; CPE synthase; Sterile alpha motif domain-containing protein 8; SAM domain-containing protein 8

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human SAMD8.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of PBGD expression in Hela (A), Raji (B), K562 (C) whole cell lysates.