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TMEM120A polyclonal antibody

货号: BS31585

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS31585

Product Name :TMEM120A polyclonal antibody

Host :Rabbit

Reactivity :Mouse

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :Transmembrane protein 120A: Multifunctional protein involved in mechanosensation, and plays an essential role in lipid metabolism and adipocyte differentiation . May function as a potential ion channel involved in sensing mechanical stimuli (By similarity). Mediates the mechanosensitivity of the PKD2-TMEM120A channel complex through direct physical interaction (By similarity). TMEM120A seems to affect mechanosensation by inhibiting PIEZO2 channels, possibly by altering cellular lipid content . TMEM120A is structurally similar to a lipid-modifying enzyme, ELOVL7, and contains a bound coenzyme A molecule, which suggests it might function as an enzyme in lipid metabolism

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of TMEM120A protein.

BiowMW :~40.8 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TMPIT; Transmembrane protein 120A; Transmembrane protein induced by tumor necrosis factor alpha

Immunogen :A synthetic peptide encompassing a sequence within the N-terminal region of human TMEM120A.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of CD223 expression in Raji (A), Ramos (B), MOLT4 (C) whole cell lysates.

免疫沉淀（IP）