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SPATA5L1 polyclonal antibody

货号: BS31525

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

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No. :BS31525

Product Name :SPATA5L1 polyclonal antibody

Swiss-Prot :Q9BVQ7

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB (1/500 - 1/1000)

Background :ATPase family gene 2 protein homolog B: ATP-dependent chaperone part of the 55LCC heterohexameric ATPase complex which is chromatin-associated and promotes replisome proteostasis to maintain replication fork progression and genome stability. Required for replication fork progression, sister chromatid cohesion, and chromosome stability. The ATPase activity is specifically enhanced by replication fork DNA and is coupled to cysteine protease-dependent cleavage of replisome substrates in response to replication fork damage. Uses ATPase activity to process replisome substrates in S-phase, facilitating their proteolytic turnover from chromatin to ensure DNA replication and mitotic fidelity . Plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles

Product :1mg/ml in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Purification&Purity :The antibody was purified by immunogen affinity chromatography.

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Recognizes endogenous levels of SPATA5L1 protein.

BiowMW :~80.7 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Spermatogenesis-associated protein 5-like protein 1

Immunogen :A synthetic peptide encompassing a sequence within the C-terminal region of human SPATA5L1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Histone H2A expression in HEK293T (A), EC9706 (B), HCT116 (C) whole cell lysates.

免疫沉淀（IP）